This publication is an educational resource for healthcare professionals focusing on the treatment of pancreatic exocrine insufficiency (PEI) with pancreatic enzyme replacement therapy (PERT). This is an under-diagnosed and under-treated condition with multiple aetiologies that can cause serious complications. To optimise treatment, it is essential that the dose of PERT is individualised according to the patient’s disease severity and adjusted according to their response. Multiple studies have shown that PERT is associated with improvements in symptoms, nutritional parameters and survival in patients with PEI. This review is supported by an educational grant from Viatris.
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